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1.
Academic Journal of Naval Medical University ; 43(11):1264-1267, 2022.
Article in Chinese | EMBASE | ID: covidwho-20244461

ABSTRACT

Objective To explore the effect of WeChat group management on blood pressure control rate and drug compliance of hypertension patients during the epidemic of coronavirus disease 2019 (COVID-19) . Methods A total of 428 consecutive patients with essential hypertension in our outpatient department from Jan. 2020 to Dec. 2020 were enrolled and randomly divided into experimental group and control group with a ratio of 1 : 1. There were 214 patients in the experimental group, 110 males and 104 females, with an average age of (55.48+/-6.11) years. There were 214 cases in the control group, 108 males and 106 females, with an average age of (56.52+/-5.19) years. WeChat groups were established for the 2 groups separately. Information on education, supervised medication and lifestyle of hypertension was provided to the patients in the experimental group through WeChat, while no active intervention was given to the control group. The blood pressure control rate and medication possession ratio (MPR) were calculated at 1, 3, 6 and 12 months of intervention, and the differences between the 2 groups were compared. Results There were no significant differences in the blood pressure control rate (91.12%195/214 vs 90.65% 194/214, 86.67%182/210vs 89.62%190/212or MPR (0.90+/-0.03 vs 0.90+/-0.05, 0.85+/-0.04 vs 0.88+/-0.03) between the 2 groups at 1 or 3 months of intervention (all P>0.05). At 6 and 12 months, the blood pressure control rate (81.73%170/208vs 88.57%186/210,75.12%154/205vs 85.99%178/207) and MPR (0.74+/-0.04 vs 0.87+/-0.05, 0.58+/-0.05 vs 0.85+/-0.03) of patients in the experimental group were significantly higher than those in the control group (all P<0.05). Conclusion During the COVID-19 epidemic, WeChat group management of hypertension patients by doctors could improve patients' blood pressure control rate and drug compliance and strengthen patients' self-management ability.Copyright © 2022, Second Military Medical University Press. All rights reserved.

2.
Mediterranean Fruits Bio-wastes: Chemistry, Functionality and Technological Applications ; : 287-302, 2022.
Article in English | Scopus | ID: covidwho-20240807

ABSTRACT

Horticultural crops, especially fruits and vegetables, are highly consumed as food and food products. These items are consumed either uncooked, partially cooked, or fully cooked, according to their nature and the cooking process. A large amount of waste is generated from fruit-and vegetable-based industries and household kitchens. According to the FAO, waste generated from fruits and vegetable processing is estimated by 25–30% of the total product. This waste is rich in active compounds and has high nutritional content. Utilization of this waste into beneficial by-products could represent an essential strategy for reducing significant dietary and economic loss as well as the negative environmental impacts. The most common wastes include pomace, peels, rind, and seeds are fabulously rich in valuable bioactive compounds such as carotenoids, enzymes, phenolics, essential oils, vitamins, and many other compounds. These bioactive compounds show their application in various industries, including food industries to develop edible films, health industries for probiotics, and other industries for valuable and natural products. The utilization of these low-cost waste for producing the high value-added product is a novel step in its sustainable utilization. Tangerine is commonly produced and consumed as fresh or processed worldwide. The Mediterranean area produces the best and high-quality tangerine in the world. It is a high vitamin C source and rich in nutrients and provides many medicinal and health benefits. According to the new information released by the FAO, considering the influences of the novel coronavirus (COVID-19), populations with extreme starvation in the world will perhaps increase. Consequently, countries should gain proficiencies and try to reduce trade-related costs, for example, by reducing food waste and losses. Therefore, the present chapter intends to summarize the different types of waste originating from Tangerine (Citrus reticula L.) and highlight their potential in developing edible films, probiotics, nanoparticles, carbon dots, microbial media, biochar, and biosorbents. © The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022.

3.
Revue Medicale Suisse ; 16(693):1014-1015, 2020.
Article in French | EMBASE | ID: covidwho-20240381
4.
Journal of Gender Studies ; : 1-11, 2023.
Article in English | Academic Search Complete | ID: covidwho-20240196

ABSTRACT

Feminist scholars and activists have long fought to make visible the fundamental but overlooked social reproduction work performed primarily by women, often in households. Taking on black feminist criticisms of the initial prioritization of the experience of white, middle-class women, these debates have developed into a broader social reproduction theory, which emphasizes the relationality of multiple forms of oppression under capitalism. The COVID-19 pandemic, with its lockdowns, temporarily turned the traditional distribution between visible and invisible work on its head when many so-called productive workers were ushered into their homes, leaving only the most essential workers publicly visible in the streets and valorized in online spaces. The sudden visibility of these generally low-paid, often racialized and marginalized workers now coded as ‘essential' highlighted the importance of the work of social reproduction. However, the category of essential workers was ambivalent, in that by making visible some forms of social reproduction it continued to obscure others, especially familial care work and housework. In this article we analyse the ambivalent category of the essential worker and argue that it exemplifies, as social reproduction theory attests, that the capitalist production process always requires invisible labour, even as some previously invisible forms become increasingly visible. [ FROM AUTHOR] Copyright of Journal of Gender Studies is the property of Routledge and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)

5.
Journal of Service Theory and Practice ; 31(2):184-202, 2021.
Article in English | APA PsycInfo | ID: covidwho-20239625

ABSTRACT

Purpose: The coronavirus (COVID-19) has had a tremendous impact on companies worldwide. However, researchers have no clear idea of the key issues requiring their attention. This paper aims to close this gap by analysing all business-related posts on a coronavirus subreddit ("r/coronavirus") and identifying the main research streams that are guiding the research agenda for a post-coronavirus world. Design/methodology/approach: We use data from reddit, particularly the subreddit "r/coronavirus" to identify posts that reveal the impact of coronavirus on business. Our dataset has more than 200,000 posts. We used an artificial intelligence-based algorithm to scrape the data with business-related search terms, clean it and analyse the discussion topics. Findings: We show the key topics that address the impact of coronavirus on business, combining them into four themes: essential service provision, bricolage service innovation, responsible shopping practices and market shaping amid crisis. We discuss these themes and use them to develop a service research agenda. The results are reported against the backdrop of service research priorities. Originality/value: The study identifies four key themes that have emerged from the impact of coronavirus on business and that require scholarly attention. Our findings can guide service research with unique insights provided immediately after the coronavirus outbreak to conduct research that matters to business and helps people in vulnerable positions in a post-coronavirus world. (PsycInfo Database Record (c) 2023 APA, all rights reserved)

6.
Journal of Transportation Engineering Part A: Systems ; 149(8), 2023.
Article in English | Scopus | ID: covidwho-20238827

ABSTRACT

The global outbreak of coronavirus disease 2019 (COVID-19) has affected the urban mobility of nations around the world. The pandemic may even have a potentially lasting impact on travel behaviors during the post-pandemic stage. China has basically stopped the spread of COVID-19 and reopened the economy, providing an unprecedented environment for investigating post-pandemic travel behaviors. This study conducts multiple investigations to show the changes in travel behaviors in the post-pandemic stage, on the basis of empirical travel data in a variety of cities in China. Specifically, this study demonstrates the changes in road network travel speed in 57 case cities and the changes in subway ridership in 26 case cities. Comprehensive comparisons can indicate the potential modal share in the post-pandemic stage. Further, this study conducts a case analysis of Beijing, where the city has experienced two waves of COVID-19. The variations in travel speed in the road network of Beijing at different stages of the pandemic help reveal the public's responses towards the varying severity of the pandemic. Finally, a case study of the Yuhang district in Hangzhou is conducted to demonstrate the changes in traffic volume and vehicle travel distance amid the post-pandemic stage based on license plate recognition data. Results indicate a decline in subway trips in the post-pandemic stage among case cities. The vehicular traffic in cities with subways has recovered in peak hours on weekdays and has been even more congested than the pre-pandemic levels;whereas the vehicular traffic in cities without subways has not rebounded to pre-pandemic levels. This situation implies a potential modal shift from public transportation to private vehicular travel modes. Results also indicate that commuting traffic is sensitive to the severity of the pandemic. This may be because countermeasures, e.g., work-from-home and suspension of non-essential businesses, will be implemented if the pandemic restarts. The travel speed in non-peak hours and on non-workdays is higher than pre-pandemic levels, indicating that non-essential travel demand may be reduced and the public's vigilance towards the pandemic may continue to the post-pandemic stage. These findings can help improve policymaking strategies in the post-pandemic new normal. © 2023 American Society of Civil Engineers.

7.
ILR Review ; 2023.
Article in English | Scopus | ID: covidwho-20235432

ABSTRACT

This article provides the first systematic assessment of the impact of COVID-19 on the labor market for immigrant workers in Europe. The authors estimate that in 2020 extra-EU migrants were twice as likely and EU migrants were 1.6 times as likely to experience employment loss relative to comparable natives. To understand the determinants of these large gaps, the article focuses on three job characteristics—essentiality, temporariness, and teleworkability—and documents that migrants were overrepresented among essential, temporary, and low-teleworkable occupations at the onset of the pandemic. The authors estimate that pre-pandemic occupational sorting accounts for 25 to 35% of the explained migrant–native gap in the risk of employment termination, while sorting into industries accounts for the rest of the explained gap. More than half of this gap remains unexplained. Although major employment losses were averted thanks to the massive use of short-time work programs in Europe, migrant workers—particularly extra-EU migrants—suffered from high economic vulnerability during the pandemic. © The Author(s) 2023.

8.
Asian Textile Journal ; 32(3-4):55-59, 2023.
Article in English | Scopus | ID: covidwho-20233289
9.
World Environmental and Water Resources Congress 2023: Adaptive Planning and Design in an Age of Risk and Uncertainty - Selected Papers from World Environmental and Water Resources Congress 2023 ; : 881-890, 2023.
Article in English | Scopus | ID: covidwho-20233168

ABSTRACT

Water distribution systems (WDSs) deliver clean, safe drinking water to consumers, providing an essential service to constituents. WDSs are increasingly at risk of contamination due to aging infrastructure and intentional acts that are possible through cyber-physical vulnerabilities. Identifying the source of a contamination event is challenging due to limited system-wide water quality monitoring and non-uniqueness present in solving inverse problems to identify source characteristics. In addition, changes in the expected demand patterns that are caused by, for example, social distancing during a pandemic, adoption of water conservation behaviors, or use of decentralized water sources can change the anticipated propagation of contaminant plumes in a network. This research develops a computational framework to characterize contamination sources using machine learning (ML) techniques and simulate water demands and human exposure to a contaminant using agent-based modeling (ABM). An ABM framework is developed to simulate demand changes during the COVID-19 pandemic. The ABM simulates population movement dynamics, transmission of COVID-19 within a community, decisions to social distance, and changes in demands that occur due to social distancing decisions. The ABM is coupled with a hydraulic simulation model, which calculates flows in the network to simulate the movement of a contaminant plume in the network for several contamination event scenarios. ML algorithms are applied to determine the location of source nodes. Research results demonstrate that ML using random forests can identify source nodes based on inline and mobile sensor data. Sensitivity analysis is conducted to explore the number of mobile sensors that are needed to accurately identify the source node. Rapidly identifying contamination source nodes can increase the speed of response to a contamination event, reducing the impact to the community and increasing the resiliency of WDSs during periods of changing demands. © World Environmental and Water Resources Congress 2023.All rights reserved

10.
Anthropology of Work Review ; 2023.
Article in English | Web of Science | ID: covidwho-20232654

ABSTRACT

As I read "Revaluing Work after COVID-19" (Collins, this issue), I wondered how was it that garment workers making the personal protective equipment (PPE) so desperately needed during the pandemic were never considered "essential workers." As governments wrestled with the need to sustain their economies while safeguarding the health of citizens, keeping health infrastructures functioning, and ensuring the basic needs of populations could be met, they had to determine whose work was "essential." As Collins (this issue) shows, these debates exceeded the "narrow technical meanings coming to signify workers who were putting their lives on the line to insure the well-being of the rest of us." Amidst celebrations of other "essential workers" and craftivists sewing masks from the comfort of their homes, the non-essential essential labor of garment workers stayed on the margins of the historical memory of COVID-19. This essay thinks with Collins to consider how garment workers got lost in between the scales of the national and transnational.

11.
The International Migration Review ; 57(2):521-556, 2023.
Article in English | ProQuest Central | ID: covidwho-20232143

ABSTRACT

Emerging evidence suggests that the COVID-19 pandemic has extracted a substantial toll on immigrant communities in the United States, due in part to increased potential risk of exposure for immigrants to COVID-19 in the workplace. In this article, we use federal guidance on which industries in the United States were designated essential during the COVID-19 pandemic, information about the ability to work remotely, and data from the 2019 American Community Survey to estimate the distribution of essential frontline workers by nativity and immigrant legal status. Central to our analysis is a proxy measure of working in the primary or secondary sector of the segmented labor market. Our results indicate that a larger proportion of foreign-born workers are essential frontline workers compared to native-born workers and that 70 percent of unauthorized immigrant workers are essential frontline workers. Disparities in essential frontline worker status are most pronounced for unauthorized immigrant workers and native-born workers in the secondary sector of the labor market. These results suggest that larger proportions of foreign-born workers, and especially unauthorized immigrant workers, face greater risk of potential exposure to COVID-19 in the workplace than native-born workers. Social determinants of health such as lack of access to health insurance and living in overcrowded housing indicate that unauthorized immigrant essential frontline workers may be more vulnerable to poor health outcomes related to COVID-19 than other groups of essential frontline workers. These findings help to provide a plausible explanation for why COVID-19 mortality rates for immigrants are higher than mortality rates for native-born residents.

12.
Molecules ; 28(11)2023 May 26.
Article in English | MEDLINE | ID: covidwho-20243101

ABSTRACT

Nowadays, due to a higher resistance to drugs, antibiotics, and antiviral medicaments, new ways of fighting pathogens are intensively studied. The alternatives for synthesized compositions are natural products, most of which have been known in natural medicine for a long time. One of the best-known and intensively investigated groups are essential oils (EOs) and their compositions. However, it is worth noting that the method of application can play a second crucial part in the effectiveness of the antimicrobial activity. EOs possess various natural compounds which exhibit antimicrobial activity. One of the compositions which is based on the five main ingredients of eucalyptus, cinnamon, clove, rosemary, and lemon is named "five thieves' oil" (Polish name: olejek pieciu zlodziei) (5TO) and is used in natural medicine. In this study, we focused on the droplet size distribution of 5TO during the nebulization process, evaluated by the microscopic droplet size analysis (MDSA) method. Furthermore, viscosity studies, as well as UV-Vis of the 5TO suspensions in medical solvents such as physiological salt and hyaluronic acid, were presented, along with measurements of refractive index, turbidity, pH, contact angle, and surface tension. Additional studies on the biological activity of 5TO solutions were made on the P. aeruginosa strain NFT3. This study opens a way for the possible use of 5TO solutions or emulsion systems for active antimicrobial applications, i.e., for surface spraying.


Subject(s)
Anti-Infective Agents , Eucalyptus , Oils, Volatile , Oils, Volatile/pharmacology , Oils, Volatile/chemistry , Anti-Infective Agents/pharmacology , Anti-Bacterial Agents/pharmacology , Anti-Bacterial Agents/chemistry , Antiviral Agents , Pseudomonas aeruginosa
13.
J Funct Biomater ; 14(5)2023 May 12.
Article in English | MEDLINE | ID: covidwho-20242478

ABSTRACT

In March 2020, the World Health Organization announced a pandemic attributed to SARS-CoV-2, a novel beta-coronavirus, which spread widely from China. As a result, the need for antiviral surfaces has increased significantly. Here, the preparation and characterization of new antiviral coatings on polycarbonate (PC) for controlled release of activated chlorine (Cl+) and thymol separately and combined are described. Thin coatings were prepared by polymerization of 1-[3-(trimethoxysilyl)propyl] urea (TMSPU) in ethanol/water basic solution by modified Stöber polymerization, followed by spreading the formed dispersion onto surface-oxidized PC film using a Mayer rod with appropriate thickness. Activated Cl-releasing coating was prepared by chlorination of the PC/SiO2-urea film with NaOCl through the urea amide groups to form a Cl-amine derivatized coating. Thymol releasing coating was prepared by linking thymol to TMSPU or its polymer via hydrogen bonds between thymol hydroxyl and urea amide groups. The activity towards T4 bacteriophage and canine coronavirus (CCV) was measured. PC/SiO2-urea-thymol enhanced bacteriophage persistence, while PC/SiO2-urea-Cl reduced its amount by 84%. Temperature-dependent release is presented. Surprisingly, the combination of thymol and chlorine had an improved antiviral activity, reducing the amount of both viruses by four orders of magnitude, indicating synergistic activity. For CCV, coating with only thymol was inactive, while SiO2-urea-Cl reduced it below a detectable level.

15.
Health Policy Plan ; 2023 May 30.
Article in English | MEDLINE | ID: covidwho-20241259

ABSTRACT

Responsive primary health-care facilities are the foundation of resilient health systems, yet little is known about facility-level processes that contribute to the continuity of essential services during a crisis. This paper describes the aspects of primary health-care facility resilience to coronavirus disease 2019 (COVID-19) in eight countries. Rapid-cycle phone surveys were conducted with health facility managers in Bangladesh, Burkina Faso, Chad, Guatemala, Guinea, Liberia, Malawi and Nigeria between August 2020 and December 2021. Responses were mapped to a validated health facility resilience framework and coded as binary variables for whether a facility demonstrated capacity in eight areas: removing barriers to accessing services, infection control, workforce, surge capacity, financing, critical infrastructure, risk communications, and medical supplies and equipment. These self-reported capacities were summarized nationally and validated with the ministries of health. The analysis of service volume data determined the outcome: maintenance of essential health services. Of primary health-care facilities, 1,453 were surveyed. Facilities maintained between 84% and 97% of the expected outpatient services, except for Bangladesh, where 69% of the expected outpatient consultations were conducted between March 2020 and December 2021. For Burkina Faso, Chad, Guatemala, Guinea and Nigeria, critical infrastructure was the largest constraint in resilience capabilities (47%, 14%, 51%, 9% and 29% of facilities demonstrated capacity, respectively). Medical supplies and equipment were the largest constraints for Liberia and Malawi (15% and 48% of facilities demonstrating capacity, respectively). In Bangladesh, the largest constraint was workforce and staffing, where 44% of facilities experienced moderate to severe challenges with human resources during the pandemic. The largest constraints in facility resilience during COVID-19 were related to health systems building blocks. These challenges likely existed before the pandemic, suggesting the need for strategic investments and reforms in core capacities of comprehensive primary health-care systems to improve resilience to future shocks.

16.
Front Public Health ; 11: 1187990, 2023.
Article in English | MEDLINE | ID: covidwho-20239583

ABSTRACT

[This corrects the article DOI: 10.3389/fpubh.2023.1074356.].

17.
Molecules ; 28(11)2023 May 24.
Article in English | MEDLINE | ID: covidwho-20238192

ABSTRACT

Essential oils (Eos) have demonstrated antiviral activity, but their toxicity can hinder their use as therapeutic agents. Recently, some essential oil components have been used within safe levels of acceptable daily intake limits without causing toxicity. The "ImmunoDefender," a novel antiviral compound made from a well-known mixture of essential oils, is considered highly effective in treating SARS-CoV-2 infections. The components and doses were chosen based on existing information about their structure and toxicity. Blocking the main protease (Mpro) of SARS-CoV-2 with high affinity and capacity is critical for inhibiting the virus's pathogenesis and transmission. In silico studies were conducted to examine the molecular interactions between the main essential oil components in "ImmunoDefender" and SARS-CoV-2 Mpro. The screening results showed that six key components of ImmunoDefender formed stable complexes with Mpro via its active catalytic site with binding energies ranging from -8.75 to -10.30 kcal/mol, respectively for Cinnamtannin B1, Cinnamtannin B2, Pavetannin C1, Syzyginin B, Procyanidin C1, and Tenuifolin. Furthermore, three essential oil bioactive inhibitors, Cinnamtannin B1, Cinnamtannin B2, and Pavetannin C, had significant ability to bind to the allosteric site of the main protease with binding energies of -11.12, -10.74, and -10.79 kcal/mol; these results suggest that these essential oil bioactive compounds may play a role in preventing the attachment of the translated polyprotein to Mpro, inhibiting the virus's pathogenesis and transmission. These components also had drug-like characteristics similar to approved and effective drugs, suggesting that further pre-clinical and clinical studies are needed to confirm the generated in silico outcomes.


Subject(s)
COVID-19 , Oils, Volatile , Humans , SARS-CoV-2 , Antiviral Agents/chemistry , Oils, Volatile/pharmacology , Molecular Docking Simulation , Protease Inhibitors/chemistry , Viral Nonstructural Proteins/metabolism , Peptide Hydrolases/metabolism , Molecular Dynamics Simulation
18.
Int J Biol Macromol ; 243: 125228, 2023 Jul 15.
Article in English | MEDLINE | ID: covidwho-20234527

ABSTRACT

Melaleuca alternifolia essential oil (MaEO) is a green antimicrobial agent suitable for confection eco-friendly disinfectants to substitute conventional chemical disinfectants commonly formulated with toxic substances that cause dangerous environmental impacts. In this contribution, MaEO-in-water Pickering emulsions were successfully stabilized with cellulose nanofibrils (CNFs) by a simple mixing procedure. MaEO and the emulsions presented antimicrobial activities against Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli). Moreover, MaEO deactivated the SARS-CoV-2 virions immediately. FT-Raman and FTIR spectroscopies indicate that the CNF stabilizes the MaEO droplets in water by the dipole-induced-dipole interactions and hydrogen bonds. The factorial design of experiments (DoE) indicates that CNF content and mixing time have significant effects on preventing the MaEO droplets' coalescence during 30-day shelf life. The bacteria inhibition zone assays show that the most stable emulsions showed antimicrobial activity comparable to commercial disinfectant agents such as hypochlorite. The MaEO/water stabilized-CNF emulsion is a promissory natural disinfectant with antibacterial activity against these bacteria strains, including the capability to damage the spike proteins at the SARS-CoV-2 particle surface after 15 min of direct contact when the MaEO concentration is 30 % v/v.


Subject(s)
Anti-Infective Agents , COVID-19 , Disinfectants , Melaleuca , Tea Tree Oil , Cellulose/chemistry , Emulsions/chemistry , SARS-CoV-2 , Escherichia coli , Staphylococcus aureus , Anti-Infective Agents/pharmacology , Water/chemistry
19.
Extr Ind Soc ; : 101284, 2023 Jun 06.
Article in English | MEDLINE | ID: covidwho-20231211

ABSTRACT

This research explores gold's safe-haven properties amid oil price instability, focusing on the COVID-19 pandemic. The study examines how gold hedges against oil price swings in the context of the pandemic's exceptional market circumstances. A VAR (Vector Autoregressive) model analyzes gold and oil prices from 2006 through 2021. The VAR model reflects the dynamic interactions and interdependencies between these two essential commodities in the context of oil price volatility and the COVID-19 pandemic. This analysis shows that gold protects against oil price volatility and the COVID-19 pandemic-gold buffers against oil price swings due to its strong inverse association with oil prices. Gold offers investors security and asset preservation during significant oil price volatility. In light of oil price volatility and the COVID-19 pandemic, the study helps explain gold's importance as a diversification tool and haven asset. Investors, policymakers, and market players should consider gold as a hedge against oil price volatility and economic instability.

20.
Public Health Pract (Oxf) ; 6: 100393, 2023 Dec.
Article in English | MEDLINE | ID: covidwho-2328209

ABSTRACT

Objectives: We aimed to evaluate a quality improvement initiative designed to control SARS-CoV-2 (COVID) using the large-scale deployment of antimicrobial photodisinfection therapy (aPDT) for nasal decolonization in a Canadian industrial workplace (a food processing plant). Study design: Using a retrospective chart review of treatment questionnaires, linked to COVID laboratory testing results, a quality improvement assessment was analyzed to determine treatment effectiveness and safety. Methods: This voluntary aPDT intervention involved the administration of a light-sensitive liquid to the nose followed by nonthermal red-light irradiation on a weekly basis. Employees in food processing industries are at increased risk for COVID infection due to the nature of their work environments. In an effort to mitigate the transmission and consequences of the disease among such workers and the community at large, aPDT was added to a well-established bundle of pre-existing pandemic safety measures (e.g., mask-wearing, testing, contact tracing, workplace-engineered barriers, increased paid sick leave). Results: From December 2020 to May 2021, we found high interest in and compliance with aPDT treatment, along with a statistically significant lower PCR test positivity rate in the study population in comparison to the case rates for the local Canadian province. Treatment safety monitoring and outcomes of the aPDT program demonstrated no serious adverse events. Conclusions: This study suggests nasal photodisinfection provides safe and effective COVID viral suppression when deployed across the majority of workers in an industrial workplace setting.

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